Kelor, Salam, Pepaya, Binahong Mystery in RNAi Indigenous Vector Transfection: a Mystic Semiconductor?
Abstract
Spinel ferrite extracted from leaves is the Next Generation (NG) drug-gene delivery, which is a prestige present by Pharma manufactures in cancer and viral diseases, but not aware of the nature physiology of orchids, leaves, and stick mantids, where the prevalence has been known high in the tropical rainforest countries. RNAi, a novel non-viral vectormediated gene delivery into mammalian cells could be for silencing, increasing gene production, or editing the gene, also occurred in the laboratory incubator or in our large huge natural incubators such as tropical rainforests at night where relative humidity near 100% and high level of CO2 more than 5%-10%, loss from leaves. This review is the first that reveal the physiology of natural nonviral vector RNAi based on cellular biophysics semiconductor truths, changing the mystic to a mystery of laden sociology and the health problem in wet and warm areas, high relative humidity condition.
Method: Review articles done from Science Direct, EBSCO-host, etc. Keywords: cobalt ferrite and Moringa, broaden with other diction found in Bayesian network.
Result: Nickel ferrites also known as one of the spinel ferrites (SF), are frequently utilized in magnetic-based drug delivery and contrast agents. Many types of methods of doping give different sizes, morphology, and physical features of magnetic NPs. All samples displayed superparamagnetic (SPM) behavior at room temperature, with no or negligible coercivity and retentivity.
Conclusions: Semiconductor CoFe2O4 extracted from many leaves from the tropical rainforest area, act as a nano-carrier of RNAi in wet and warm tropical rainforest countries, are signed by mantids.
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Introduction
Binahong1 (Anredera cordifolia) heart leaf, Salam (Syzygium polyanthum) bay leaf,2 Papaya (Carica papaya), Kelor (Moringa oleifera)3,4,5 drumstick tree leaves extraction, is a Next Generation (NG) of nonviral vector-mediated gene delivery into mammalian cells.6,7,8 CoFe2O4 (cobalt ferrite, CF) nanoparticle 9 and nickel ferrite (NiFe2O4, NiF),10 is potentially superparamagnetic nanoparticles, act as a semiconductor which has electromagnetic power.
Besides gene delivery into mammalian cells, cobalt NPs also used in silencing, increasing expression of genes, and editing CRISPR/Cas9 of virus infection therapy.11
RNAi, a novel non-viral vector-mediated gene delivery into mammalian cells12 could be for silencing, increasing gene production, or editing the gene, which could be occurred in a laboratory incubator, or in our large huge natural incubator such as tropical rainforest at night where relative humidity near 100% and high level of CO2 more than 5-10%, by which CO2 loss from leaves. That’s why living plants could not place in the bedroom at night. This review is the first revealed natural nonviral vector RNAi based on cellular biophysics semiconductor NPs, open the mysticism and mystery of laden sociology and laden health problem in tropical rainforests hidden by stigma, mysticism, and sensitiveness by the family, or even by the village.13
Conclusion
Semiconductor CoFe2O4 extracted from many leaves from the tropical rainforest area, act as a nano-carrier transposon bullet in the transfection process in wet and warm tropical rainforest countries, are signed by mantids. Improving the performance of the Nano Ferrite Indigenous Vector in various places, and various parts of plants will develop the knowledge for prospects to further enrichments.